Tributyrin is emulsified from butyric acid and glycerin, does not decompose in gastric juice, slowly releases into butyric acid and glycerol under the action of pancreatic lipase, repairs intestinal villi, inhibits intestinal harmful bacteria, and promotes nutrients. Absorption and utilization. The use of tributyrin in young animals has the effect of reducing diarrhea after weaning in young animals, reducing weaning stress, increasing survival rate and increasing daily weight.

Synonyms: glyceryl tributyrate
Molecular Formula: C15H26O6
Molecular Weight: 302.36
Cas No.: 60-01-5

WHOLESALE PRICE CHINA 50% TRIBUTYRIN COATED

Tributyrin Specification:

Tributyrin Mainly used in the manufacture of food, soap, candles, etc., also used as a solvent.
Tributyric acid glyceride does not decompose in gastric juice, and slowly releases into butyric acid and glycerin under the action of pancreatic lipase, repairs intestinal villi, inhibits intestinal harmful bacteria, and promotes the absorption and utilization of nutrients.
The use of tributyrin in young animals has the effect of reducing diarrhea after weaning in young animals, reducing weaning stress, increasing survival rate and increasing daily weight.
Its main uses in animal husbandry can be summarized as:
1, all over the stomach – 100% over the stomach;
2, anti-intestinal – the intestine effectively absorb at least 100ppm butyric acid to prevent colonic vegetative diarrhea and proliferative ileitis;
3, the protective mucosa – the fore intestine, the midgut, the hindgut three points evenly absorbed, effectively repair intestinal mucosal damage, comprehensive protection of the intestinal mucosa;
4, promote lactation – increase feed intake of sows, promote sow lactation;
5, fast energy supply – provide rapid energy for intestinal mucosal cells, promote the rapid growth and development of intestinal mucosa;
6, long and neat – to promote weaned piglets to eat, improve the absorption of nutrients, significantly improve the uniformity of the pigs.
Mechanism of action:
The intestinal mucosa has a physiological function of absorbing nutrients and an immune barrier. Modern nutritional physiology studies have shown that the mucosal barrier plays a key role in nutrient absorption and disease prevention and control. The morphology, structure and function of animal intestinal mucosa are influenced by many factors, such as animal age, nutrition, pathogenic microorganisms and environment. In the young animal stage, the structure and function of the intestinal mucosa are not well developed. Some stress factors (such as weaning) also significantly affect the structure and function of the intestinal mucosa, leading to the destruction of the intestinal mucosal barrier, ultimately affecting the health of the animal and Growing.

The intestinal mucosa is the fastest growing tissue in the early stage of animal growth and one of the fastest-renewing tissues in animals. Rapid growth and development require constant energy and various nutrients. Therefore, the intestinal mucosa is the most sensitive tissue to the nutrients in animals. The repair of intestinal mucosal damage caused by some stress factors (such as weaning) requires energy and nutrients. Pigs are used to maintain the required energy, with approximately 24% of the intestines. Intestinal epithelial renewal involves the migration of mucosal cells, ie the migration of cells from the crypt to the villi, which is an energy-consuming process. Reducing the renewal of intestinal epithelial cells will save energy for growth, and effective energy is a guarantee for normal renewal of the intestinal epithelium.
The functional unit of the small intestine is the villus, the functional cell of the villus. The intestinal epithelial cells originate from different crypt cells. In the crypt, the intestinal epithelial cells are secreted. When it migrates to the side of the villi, it matures into the absorbed villus cells. The microvilli become longer and the number of cells increases. If the villus top is damaged, the mature absorbed cells are lost, and the immature crypt cells produce a net secretion consequence, resulting in a severe digestive absorption disorder of the villus cells. Histologically, the shortening and fusion of the villi is called “fluff atrophy”, which leads to a decrease in the functional surface area of ​​the mucosa and a decrease in the absorption capacity, resulting in diarrhea in the piglets.
The underlying cause of changes in the structure of the small intestine villi is that the supply of effective energy of the mucosal cells is insufficient, which inevitably leads to endogenous “starvation” of the intestinal cells, which cannot maintain normal renewal and repair of tissue damage.
Early weaning of piglets due to a series of stress factors including physiological, psychological, environmental and nutritional factors (such as feed antigens), leading to intestinal structural and functional damage, such as intestinal villus atrophy and crypt hyperplasia; digestive enzyme activity decreased, Reduced immune function; decreased digestion and absorption capacity of the small intestine. Production is characterized by decreased feed intake, growth retardation and diarrhea. A good diet must be provided to solve these problems. A good diet composition can reduce the energy required for intestinal mucosal cell migration, provide effective energy nutrition, and repair intestinal structural and functional damage caused by weaning stress.
Tributyl glyceride does not decompose in gastric juice and slowly releases into butyric acid and glycerol under the action of intestinal lipase. Butyric acid is a short-chain fatty acid, which is the main source of energy for intestinal epithelial cells. It can significantly stimulate the proliferation of intestinal epithelial cells and increase the height of small intestine villi, thereby promoting nutrient absorption, enhancing immunity and improving animal health, thus overcoming weaning stress in piglets. Syndrome, improve production performance and reduce mortality.

How Can Tributyrin Improve Digestive Health and Gut Function? 

Maintaining optimal gut health is essential for overall wellness, and tributyrin has emerged as a key functional ingredient that supports intestinal integrity and digestive efficiency. This naturally occurring triglyceride, composed of butyric acid esters, is widely recognized for its role in nourishing the intestinal lining and modulating the gut microbiome. Supplementing with tributyrin supplement can enhance nutrient absorption and promote the growth of beneficial bacteria, such as Lactobacillus and Bifidobacterium, which are critical for balanced gastrointestinal function.

Scientific studies indicate that tributyrin for gut health helps maintain mucosal barrier integrity, reduces inflammation, and contributes to overall gut homeostasis. The compound works effectively when integrated into dietary regimens or functional foods, providing sustained release of butyrate in the colon. Certain formulations, such as corebiome tributyrin, are specifically engineered to maximize bioavailability and targeted delivery to the lower intestines, ensuring efficient utilization by gut epithelial cells.

Additionally, tributyrin benefits extend to metabolic health, as butyrate plays a role in energy metabolism and immune regulation. Companies sourcing tributyrin 350 or other high-purity forms report consistent quality in both research and commercial applications. The use of tributyrin as corebiome products allows food and supplement manufacturers to offer science-backed gut health solutions that are increasingly in demand in health-conscious markets. Whether incorporated into capsules, powders, or functional foods, tributyrin provides a natural, evidence-based approach to improving intestinal health, supporting digestion, and enhancing overall quality of life for consumers of all ages. Its inclusion in modern dietary strategies represents a shift towards preventive and restorative nutrition, aligning with global trends in gut microbiome research and functional wellness.

What Are the Industrial and Supplement Applications of Tributyrin? 

Tributyrin is not only valued for its gut health properties but also for its versatility in industrial, pharmaceutical, and supplement applications. In the feed industry, it serves as a nutritional enhancer, supporting intestinal health in livestock and poultry, which contributes to improved weight gain, feed efficiency, and overall animal wellbeing. Certain products, such as tributyrin x and tributyrin as corebiome ™, have been designed for high bioavailability and stability during feed processing. These forms resist breakdown in acidic environments, ensuring targeted delivery to the intestines.

In the human supplement market, tributyrin supplement is formulated into capsules, powders, and functional beverages that allow convenient daily intake. Scientific evidence shows that tributyrin uses extend beyond gut integrity; it supports anti-inflammatory pathways, enhances mucosal barrier protection, and modulates short-chain fatty acid production. Manufacturers and suppliers investing in tributyrin factory quality products benefit from consistent chemical purity, traceability, and regulatory compliance, which are critical for international distribution.

Additionally, tributyrin price remains competitive considering its high potency and multifunctional applications. As functional nutrition trends continue to rise, corebiome tributyrate and other bioengineered forms of tributyrin are increasingly incorporated into gut-targeted supplements, prebiotic formulations, and clinical nutrition products. This adaptability makes it an essential ingredient for R&D teams seeking scientifically validated solutions for both human and animal health. Its stability, ease of formulation, and demonstrated health benefits position tributyrin as a cornerstone compound in modern nutrition and functional food innovation.

Why Is Tributyrin Considered a Key Functional Ingredient in Health Products? 

In recent years, tributyrin has gained recognition as a functional ingredient with significant health implications. Its primary mechanism involves the controlled release of butyrate, a short-chain fatty acid essential for intestinal cell energy and immune modulation. Research highlights that tributyrin health benefits include supporting epithelial integrity, reducing systemic inflammation, and promoting balanced gut microbiota. The availability of high-quality tributyrin suppliers and tributyrin manufacturers allows companies to formulate supplements, nutraceuticals, and functional foods with precise dosing and consistent efficacy.

Formulations like corebiome tributyrin leverage proprietary delivery technologies to ensure maximum absorption in the distal colon, which enhances its physiological impact. Additionally, tributyrin 350 and other coated forms provide stability during storage and processing, preventing premature degradation. Consumers using tributyrin supplement report improved digestion, enhanced metabolic balance, and positive effects on gut-related discomfort. From a commercial standpoint, tributyrin price reflects both its functional potency and the research-backed benefits it provides, making it an attractive ingredient for health-focused brands. Its multifaceted properties allow integration into diverse product formats, including powders, capsules, and liquid concentrates, catering to both B2B and direct-to-consumer markets.

The consistent quality, measurable health effects, and broad application potential make tributyrin a cornerstone in the development of next-generation gut health products and functional nutrition solutions. Companies leveraging its benefits gain a competitive edge in the expanding global market for evidence-based wellness products, aligning innovation with consumer demand for safe, effective, and scientifically validated ingredients.