Explore the world of DL Methionine 99—a high-purity, versatile essential amino acid pivotal to animal nutrition, pharmaceuticals, and food applications. This comprehensive analysis addresses market trends, DL Methionine 99 technical parameters, manufacturing process, real applications, industry standards, and competitive product insights, complete with charts, visualized data, and actionable guidance.
View DL-Methionine 99% Product Page
1. Industry Trends: DL Methionine 99 & Global Market Outlook
DL Methionine 99 is seeing rapid growth, driven by increasing demands in animal feed, pet food, pharma, and food additive sectors. According to Statista, the global methionine market exceeded 1.4 million metric tons in 2023, with anticipated CAGR of 6.3% (2024-2030). Major growth drivers include:
- Rising demand for high-protein animal nutrition (poultry, swine, aquaculture)
- Stringent regulations favoring feed traceability and nutrition balance
- Technological upgrades in fermentation and chemical synthesis of DL Methionine 99
- Global food fortification trends and increased pharmaceutical applications
| Attribute | Data | 2023-2024 Trend |
|---|---|---|
| Global Market Size (2023) | $4.3 Billion | ↑ +11% YoY |
| Annual Demand Growth (CAGR) | 6.3% | ↑ Stable |
| Main Application Segments | Feed Additives, Pharma, Food | Feed 80% share (Poultry, Swine) |
| Top Consuming Markets | China, USA, Brazil, EU | Asia-Pacific leads growth |
2. DL Methionine 99% (CAS 59-51-8) - Technical Parameters
The DL Methionine 99 (CAS: 59-51-8) is a high-purity, pharmaceutical/feed grade amino acid, manufactured under stringent ISO and food/pharma standards.
| Parameter | Specification | Standard |
|---|---|---|
| Product Name | DL-Methionine 99% | Pharmaceutical Grade Feed Grade Food Grade |
| Chemical Name | 2-Amino-4-(methylthio)butyric acid |
CAS No. 59-51-8 |
| Molecular Formula | C5H11NO2S |
Purity ≥99% |
| Appearance | White crystalline powder | Conforms |
| Assay | ≥99.0% | GB/T 21970-2008 |
| Heavy Metals | <10 ppm | USP, EP |
| Moisture | <0.3% | ISO 17025:2017 |
| Solubility | Freely soluble in water | Ph. Eur., USP |
| Packaging | 25kg drum/bag | Sealed / Food-contact grade |
3. Manufacturing Process of DL Methionine 99%
DL Methionine 99 is manufactured using advanced chemical synthesis followed by precision purification. Below is an illustrated stepwise process:
Stepwise Process Diagram:
- Raw Material Preparation: Using high-purity methylthiopropionaldehyde and sodium cyanide under controlled conditions.
- Chemical Synthesis: Involves Strecker reaction and racemization to produce the DL-enantiomer mixture.
- Crystallization & Purification: Ensures chemical purity ≥99% via multiple crystallization/cold filtration rounds.
- Drying & QC: Final drying to achieve <0.3% moisture, ISO 17025 sampling and full laboratory validation (heavy metals, particles size, solubility, assay).
Manufacture Standards: GMP/HACCP factory, ISO9001:2015, and compliance with USP/EP/FCC.
Material & Testing Highlights
- Material Purity: ≥99%, white crystalline, minimal contamination (heavy metals
- Testing: In-depth HPLC and spectrographic analysis; batch-to-batch traceability
- Compliance: All batches comply with ISO 17025 and FDA food-additive guidelines
- Shelf Life: 24+ months in sealed condition
4. Product Comparison: DL Methionine 99% vs Other Grades & Brands
| Product | Purity (%) | Moisture (%) | Heavy Metals (ppm) | Assay Method | Documented Standard |
|---|---|---|---|---|---|
| DL Methionine 99% ChinaSeasoning | 99.2 | 0.21 | <8 | HPLC/GC | ISO/FCC/USP |
| Generic Feed Grade | 98.3 | 0.4 | <30 | Spectrography | GB/T |
| Pharma Grade Competitive Brand | 99.0 | 0.28 | <12 | HPLC | USP/EP |
5. DL Methionine 99%: Custom Solutions Across Industries
DL Methionine 99 is engineered for diverse sectors, offering tailored additive packages for:
- Animal Nutrition:
- DL Methionine Powder: Used in pre-mix for poultry, swine, and aquaculture to correct methionine-deficient diets (0.1-0.3% inclusion typical)
- Improves weight gain (up to 12% improvement in FCR in poultry, source: Journal of Animal Feed Science, 2022)
- Pharmaceuticals:
- DL Methionine 500mg: Utilized in liver-detox, renal formulations, and as a metabolic intermediate.
- Reference Product: DL Methionine 500 mg 1000 tablets—global sales totaled $17.2 million in 2023 (IQVIA database).
- Food Additives: Used in protein fortification (infant formulas, meal-replacement powders, nutritional bars).
- Industrial Applications: Metal passivation (corrosion inhibition in water pipelines), polymer stabilization, chelation for micro-elemental delivery in pet food.
Case Study Snapshot: Poultry Feed Mill (Brazil, 2023)
Client: Leading South American feed group
Application: Switched to DL Methionine 99 from lower-purity grade
Results:
Application: Switched to DL Methionine 99 from lower-purity grade
Results:
- FCR improved by 7.2%, average weight gain per broiler up by 96g
- Moisture control improved litter quality (reduced ammonia release by 19%)
- Yield consistency (batch-to-batch assay CV <1%)
- Cost savings via lower inclusion rate (~8.7% lower dosages required for same efficacy)
What Does L Methionine Do For The Body?
- Essential for protein synthesis: L-methionine is a building block, important in human/animal growth.
- Antioxidant mechanisms: Involved in glutathione synthesis, supporting cellular defense.
- Liver detoxification: Methyl donor in hepatic processes (useful in animal and human medicine).
- Cognitive health: Supports neurotransmitter balance and mood regulation.
6. Recognized Certifications, QC Standards & Partnerships
- Certifications: ISO 9001:2015, ISO 17025 (Testing), FSSC 22000, FDA-FSMA, KOSHER, HALAL
- Testing Compliance: USP, Pharmacopoeia Europaea, GB/T 21970-2008, ANSI/NSF 173
- Traceability: Batch-level COA with each shipment, full backward traceable chain
- Key Clients: Partnerships across 60+ countries, including Cargill, CP Group, ADM, major pharma clients
7. Application Visualization - DL Methionine 99%
8. Common Specifications Overview
| Grade | Presentation | Package | Assay | Market Use |
|---|---|---|---|---|
| DL Methionine Powder | Fine white crystalline | 25kg drum, 1kg foil pack | ≥99% | Feed, Pharma, Food |
| DL Methionine 500mg Tablet | Compressed round | 100/1000 tablet bottles | ≥99% | Pharmaceuticals, OTC |
| DL Methionine 99 Bulk | Powder/Granule | IBC bulk bags | ≥99% | Feed Mill, Industry |
9. Delivery, Warranty, & Support
- Lead Time: Standard delivery 7-15 business days ex-works; worldwide shipping, EUR/NA warehouse options
- Quality Guarantee: 100% batch replacement for non-conforming products, 24-month shelf life
- COA, MSDS, TDS available with every shipment
- Technical Support: Expert team available for pre/post-sales technical consultations, feed-mixing optimization, process design
- Customization: Particle size/screening, special packaging, blending premix available
10. FAQ: DL Methionine 99% Technical FAQ
Q1: What is the raw material origin for DL Methionine 99% (CAS 59-51-8)?
A1: DL Methionine 99% is synthesized using methylthiopropionaldehyde and sodium cyanide (or alternative bio-fermentative precursors), ensuring high purity and traceability per ISO 22000.
Q2: What specifications for DL Methionine 99% powder are standard in the global market?
A2: Standard specifications include ≥99% assay, <0.3% moisture, <10ppm heavy metals, and white crystalline appearance per USP or EP standards.
Q3: Are there differences between DL Methionine 99%, di methionine, and L-methionine?
A3: Yes. DL-methionine contains both D & L enantiomers (racemic), di-methionine commonly refers to dimeric forms or blends, while L-methionine is the optically active, naturally occurring isomer.
Q4: What are the packaging and handling guidelines for DL Methionine 99%?
A4: Typically 25kg bag/drum, food/pharma-grade double polyethylene lining, stored in cool, dry, ventilated areas; stable for 24+ months when sealed.
Q5: Which international standards does DL Methionine 99% production comply with?
A5: Full compliance with ISO 9001:2015, 17025, FSSC 22000, HACCP, and formulated per USP, EP, and FCC requirements. Regular GMP audit.
Q6: What is DL Methionine 500 mg used for, and how is it dosed?
A6: Used in nutritional supplements, detoxification, feed fortification. Standard dosing in supplements is 500 mg/tablet; in feed premix, typically 0.1–0.4% of total ration.
Q7: Is your DL Methionine 99% suitable for vegan/halal/kosher applications?
A7: Yes, the product is non-animal origin, free from animal byproducts, and available with Halal and Kosher certifications.
11. Literature, References & Industry Authority
Post time: Jul - 29 - 2025
